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Article

Loss of GATA4 C-Terminus by p.S335X Mutation Modulates Coronary Artery Vascular Smooth Muscle Cell Phenotype.

Mediators of inflammation - 1 Jan 2021

Yu Ting-Yan, Chen Xin-Xin, Liu Qing-Wen, Ma Fang-Fang, Huang Hong-Lang, Zhou Lei, Zhang Wei

Abstract excerpt

Coronary artery disease (CAD) has been the leading cause of morbidity and mortality worldwide, and its pathogenesis is closely related with the proliferation and migration of vascular smooth muscle cell (VSMC). We previously reported a truncated GATA4 protein lacking C-terminus induced by p.S335X mutation in cardiomyocyte from ventricular septal defect (VSD) patients. However, it is still unclear whether GATA4...

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Identifiers

PMID: 34545275
DOI: 10.1155/2021/3698386
PMCID: PMC8449727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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