Article
MYOSLID Is a Novel Serum Response Factor-Dependent Long Noncoding RNA That Amplifies the Vascular Smooth Muscle Differentiation Program.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2016
Zhao Jinjing, Zhang Wei, Lin Mingyan, Wu Wen, Jiang Pengtao, Tou Emiley, Xue Min, Richards Angelene, Jourd'heuil David, Asif Arif, Zheng Deyou, Singer Harold A, Miano Joseph M, Long Xiaochun
Abstract excerpt
OBJECTIVE: Long noncoding RNAs (lncRNA) represent a growing class of noncoding genes with diverse cellular functions. We previously reported on SENCR, an lncRNA that seems to support the vascular smooth muscle cell (VSMC) contractile phenotype. However, information about the VSMC-specific lncRNAs regulated by myocardin (MYOCD)/serum response factor, the master switch for VSMC differentiation, is unknown. APPROACH...
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