Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-grade serous ovarian cancer: the clone wars

2 Feb 2017

Abstract excerpt

BACKGROUND: The last 5 years' studies using next-generation sequencing provided evidences that many types of solid tumors present spatial and temporal genetic heterogeneity and are composed of multiple populations of genetically distinct subclones that evolve over time following a pattern of branched evolution. The evolutionary nature of cancer has been proposed as the major contributor to drug resistance and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Ovarian cancer diagnosis and treatment
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28154920
DOI: 10.1007/s00404-017-4292-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-grade serous ovarian cancer: the clone warsPMID 28154920Read ↗

Evolutionary perspectives, heterogeneity and ovarian cancer: a complicated tale from past to presentSemantic proximity Read ↗

Evolutionary states and trajectories characterized by distinct pathways stratify ovarian high-grade serous carcinoma patientsSemantic proximity Read ↗

Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinomaSemantic proximity Read ↗

Dualistic classification of high grade serous ovarian carcinoma has its root in spatial heterogeneity.Semantic proximity Read ↗

Tumor evolution and chemoresistance in ovarian cancerSemantic proximity Read ↗

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.Semantic proximity Read ↗

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.Semantic proximity Read ↗

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.Semantic proximity Read ↗

Overview of Tumor Heterogeneity in High-Grade Serous Ovarian Cancers.Semantic proximity Read ↗

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinomaSemantic proximity Read ↗

The mutation and clonality profile of genomically unstable high grade serous ovarian cancer is established early in tumor development and conserved throughout therapy resistanceSemantic proximity Read ↗

Evolutionary mode and timing of dissemination of high-grade serous carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.