Article

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma

2019-02-19

Abstract excerpt

Multiple studies have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but these have yet to impact clinical practice. Interpretation and translation of HGSOC subtypes are complicated by tumor evolution and polyclonality accompanied by accumulation of somatic aberrations, varying cell type admixtures, and different tissues of origin. The chronology of HGSOC subtype evolution was ex...

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Literature Corpus work: 15c1ade0-b001-509d-a92d-4156a6950a1c
DOI: 10.1101/554394

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