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Article

Characterization of contrasting features between hepatitis B virus genotype A and genotype D in small envelope protein expression and surface antigen secretion.

Virology - 1 Mar 2017

Zhang Fei, Tang Xiaoli, Garcia Tamako, Lok Anna S, Wang Yongxiang, Jia Haodi, Qin Yanli, Chen Chaoyang, Wen Yumei, Li Jisu, Tong Shuping

Abstract excerpt

Hepatitis B virus (HBV) genotypes A and D are prevalent in many parts of the world and show overlapping geographic distributions. We amplified the entire HBV genome from sera of patients with genotypes A and D and generated overlength constructs for transient transfection into Huh7 or HepG2 cells. Genotype D clones were associated with less HBsAg in culture supernatant and even less intracellular HBsAg. They...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hep G2 Cells

Share to Hepatitis B Surface Antigens

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Share to Promoter Regions, Genetic

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Share to Viral Envelope Proteins

Source

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Identifiers

PMID: 28126637
DOI: 10.1016/j.virol.2017.01.009
PMCID: PMC5325793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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