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Article

Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.

Viruses - 2 Apr 2021

Zhang Jing, Wang Yongxiang, Fu Shuwen, Yuan Quan, Wang Qianru, Xia Ningshao, Wen Yumei, Li Jisu, Tong Shuping

Abstract excerpt

Hepatitis B virus (HBV) expresses co-terminal large (L), middle (M), and small (S) envelope proteins. S protein drives virion and subviral particle secretion, whereas L protein inhibits subviral particle secretion but coordinates virion morphogenesis. We previously found that preventing S protein expression from a subgenomic construct eliminated M protein. The present study further examined impact of S protein on...

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Identifiers

PMID: 33918367
DOI: 10.3390/v13040613
PMCID: PMC8065445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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