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Biological Characterization of Hepatitis B virus Genotypes: Their Role in Viral Replication and Antigen Expression

4 Nov 2021

Abstract excerpt

Hepatitis B virus (HBV) inter-host evolution has resulted in genomic diversification reflected in the existence of nine genotypes (A-I) and numerous subgenotypes. There is growing evidence that genotypes influence HBV natural history, clinical outcomes, and treatment response. However, the biological characteristics underlying these differences have not yet been established. By transfecting HuH-7 cells with...

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PMID: 34803982
DOI: 10.3389/fmicb.2021.758613

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