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Article

Characterization of two hepatitis B virus populations isolated from a hepatitis B surface antigen-negative patient.

Hepatology (Baltimore, Md.) - 1 May 2002

Jeantet Damien, Chemin Isabelle, Mandrand Bernard, Zoulim Fabien, Trepo Christian, Kay Alan

Abstract excerpt

In a study of surface antigen-negative, but weakly hepatitis B virus (HBV) DNA-positive, patients, we were able to amplify and clone whole HBV genomes from the serum of a cirrhotic patient. Sequencing showed that the patient harbored two different HBV populations, one of genotype A and the other of genotype D, with the genotype D genome apparently predominating. The surface antigen of the genotype A virus is...

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Identifiers

PMID: 11981772
DOI: 10.1053/jhep.2002.32710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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