Article
Clinical implications of DNMT3A mutations in a Southeast Asian cohort of acute myeloid leukaemia patients.
Journal of clinical pathology - 1 Aug 2017
Tan Marcus, Ng Isaac K S, Chen Zhaojin, Ban Kenneth, Ng Christopher, Chiu Lily, Seah Elaine, Lin Mingxuan, Tai Bee Choo, Yan Benedict, Ng Chin Hin, Chng Wee-Joo
Abstract excerpt
AIMS: In recent years, genomic technologies have enabled the identification of mutations in acute myeloid leukaemia (AML). DNMT3A is a recurrently mutated epigenetic modifier gene in AML. To date, the prognostic significance of DNMT3A mutations has not been studied in a Southeast Asian AML population. We sought to investigate the clinical implications of DNMT3A mutations in a Southeast Asian cohort of AML...
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