Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic significance of DNMT3A mutations in patients with acute myeloid leukemia.

Blood cells, molecules & diseases - 1 Jan 2015

Ibrahem Lamia, Mahfouz Rabab, Elhelw Loie, Abdsalam Eman M, Soliman Rehan

Abstract excerpt

Acute myeloid leukemia (AML) represents a heterogeneous group of malignancies with great variability in clinical course and response to therapy. Several molecular markers have been described that help to classify AML patients into risk groups. Mutations in DNA methyltransferase 3A (DNMT3A) gene were recently demonstrated in AML. Approximately 20% patients with AML carry DNMT3A gene mutations and were associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Disease-Free Survival
Share to DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methyltransferase 3A

Share to DNA Mutational Analysis

Share to Leukemia, Myeloid, Acute

Share to Survival Rate

Source

Identifiers

PMID: 25172541
DOI: 10.1016/j.bcmd.2014.07.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic significance of DNMT3A mutations in patients with acute myeloid leukemia.PMID 25172541Read ↗

DNMT3A mutation is a poor prognosis biomarker in AML: results of a meta-analysis of 4500 AML patients.Semantic proximity Read ↗

Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.Semantic proximity Read ↗

Acute myeloid leukemia with DNMT3A mutations.Semantic proximity Read ↗

Association between DNMT3A mutations and prognosis of adults with de novo acute myeloid leukemia: a systematic review and meta-analysis.Semantic proximity Read ↗

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications.Semantic proximity Read ↗

Significance of targeting DNMT3A mutations in AML.Semantic proximity Read ↗

Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.Semantic proximity Read ↗

DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemiaSemantic proximity Read ↗

Characteristics of DNMT3A mutations in acute myeloid leukemiaSemantic proximity Read ↗

DNMT3A in haematological malignancies.Semantic proximity Read ↗

[DNMT3A gene mutations in acute myeloid leukemia].Semantic proximity Read ↗

[Effects of DNMT3A gene mutations on prognosis of patients with acute myeloid leukemia: a meta-analysis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.