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DNMT3A mutation is a poor prognosis biomarker in AML: results of a meta-analysis of 4500 AML patients.

Leukemia research - 1 Nov 2013

Shivarov Velizar, Gueorguieva Ralitza, Stoimenov Angel, Tiu Ramon

Abstract excerpt

Somatic DNA methyl transferase 3A (DNMT3A) mutations have been recognized recently as recurrent molecular aberrations in acute myeloid leukemia (AML). The precise role of these mutations in leukemogenesis remains elusive but a number of studies have already been conducted to study their potential prognostic value in AML patients with variable results. We performed a meta-analysis on published data from over 4500...

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Identifiers

PMID: 23962568
DOI: 10.1016/j.leukres.2013.07.032

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ELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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