Article
Acute myeloid leukemia with DNMT3A mutations.
Leukemia & lymphoma - 1 Sept 2014
Li Yunlong, Zhu Baosheng
Abstract excerpt
Acute myeloid leukemia (AML), a type of blood cancer, is characterized by an increase in the number of abnormal white blood cells in the bone marrow, frequently causing hematopoietic insufficiency. It is a heterogeneous disease featuring cytogenetic aberrations, recurrent somatic mutations and alterations in gene expression. DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A) is closely associated with...
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