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Article

Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans.

Experimental gerontology - 1 Jan 2017

Ihara Akiko, Uno Masaharu, Miyatake Koichi, Honjoh Sakiko, Nishida Eisuke

Abstract excerpt

Cholesterol has attracted significant attention as a possible lifespan regulator. It has been reported that serum cholesterol levels have an impact on mortality due to age-related disorders such as cardiovascular disease. Diet is also known to be an important lifespan regulator. Dietary restriction retards the onset of age-related diseases and extends lifespan in various organisms. Although cholesterol and...

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PMID: 27989925
DOI: 10.1016/j.exger.2016.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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