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Article

DAF-16/FOXO Transcription Factor in Aging and Longevity

23 Aug 2017

Abstract excerpt

Aging is associated with age-related diseases and an increase susceptibility of cancer. Dissecting the molecular mechanisms that underlie aging and longevity would contribute to implications for preventing and treating the age-dependent diseases or cancers. Multiple signaling pathways such as the insulin/IGF-1 signaling pathway, TOR signaling, AMPK pathway, JNK pathway and germline signaling have been found to be...

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PMID: 28878670
DOI: 10.3389/fphar.2017.00548

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