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Article

Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans.

European journal of nutrition - 1 Apr 2018

Nakatani Yumiko, Yaguchi Yukie, Komura Tomomi, Nakadai Masakazu, Terao Kenji, Kage-Nakadai Eriko, Nishikawa Yoshikazu

Abstract excerpt

PURPOSE: Sesamin, a polyphenolic compound found in sesame seeds, has been reported to exert a variety of beneficial health effects. We have previously reported that sesamin increases the lifespan of Caenorhabditis elegans. In this study, we investigated the molecular mechanisms underlying the longevity effect of sesamin in C. elegans. METHODS: Starting from three days of age, Caenorhabditis elegans animals were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28239780
DOI: 10.1007/s00394-017-1396-0

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SIRT1

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