Article
Neutralizing and enhancing antibody responses to five genotypes of dengue virus type 1 (DENV-1) in DENV-1 patients.
The Journal of general virology - 1 Feb 2017
Yamanaka Atsushi, Moi Meng Ling, Takasaki Tomohiko, Kurane Ichiro, Konishi Eiji
Abstract excerpt
Dengue virus (DENV) has four distinct serotypes, DENV-1-4, with four to six genotypes in each serotype. The World Health Organization recommends tetravalent formulations including one genotype of each serotype as safe and effective dengue vaccines. Here, we investigated the impact of genotype on the neutralizing antibody responses to DENV-1 in humans. Convalescent sera collected from patients with primary...
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