Article
Conservation of the DENV-2 type-specific and DEN complex-reactive antigenic sites among DENV-2 genotypes.
Virology - 20 Jan 2012
Pitcher Trevor J, Gromowski Gregory D, Beasley David W C, Barrett Alan D T
Abstract excerpt
The envelope (E) protein is composed of three domains (ED1, ED2 and ED3) with ED3 targeted by the most potent neutralizing antibodies. DENV-2 strains can be divided into six genotypes. Comparison of ED3 of representative strains of the six genotypes revealed that there are nine variable residues...
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