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Article

Serotype-Specific Host Responses in Rhesus Macaques after Primary Dengue Challenge

24 Sept 2013

Abstract excerpt

Dengue virus (DENV) is considered to be the most important arthropod-borne viral disease and causes more than 100 million human infections annually. To further characterize primary DENV infection in vivo, rhesus macaques were infected with DENV-1, DENV-2, DENV-3, or DENV-4 and clinical parameters, as well as specificity and longevity of serologic responses, were assessed. Overt clinical symptoms were not present...

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PMID: 24062475
DOI: 10.4269/ajtmh.13-0145

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