Article
The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population.
Oncotarget - 27 Dec 2016
Balasus Daniele, Way Michael, Fusilli Caterina, Mazza Tommaso, Morgan Marsha Y, Cervello Melchiorre, Giannitrapani Lydia, Soresi Maurizio, Agliastro Rosalia, Vinciguerra Manlio, Montalto Giuseppe
Abstract excerpt
Hepatocellular carcinoma (HCC) has one of the worst prognoses amongst all malignancies. It commonly arises in patients with established liver disease and the diagnosis often occurs at an advanced stage. Genetic variations, such as single nucleotide polymorphisms (SNPs), may alter disease risk and thus may have use as predictive markers of disease outcome. The aims of this study were (i) to assess the association...
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