Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HCC and liver disease risks in homozygous PNPLA3 p.I148M carriers approach monogenic inheritance

2 Jan 2015

Abstract excerpt

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinomaJournal of HepatologyVol. 61Issue 1PreviewSubtle inter-patient genetic variation and environmental factors combine to determine disease progression in non-alcoholic fatty liver disease (NAFLD). Carriage of the PNPLA3 rs738409 c.444C >G minor allele (encoding the I148M...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folate and B Vitamins Research

Share to Liver Disease Diagnosis and Treatment

Source

Identifiers

PMID: 25559327
DOI: 10.1016/j.jhep.2014.10.048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HCC and liver disease risks in homozygous PNPLA3 p.I148M carriers approach monogenic inheritancePMID 25559327Read ↗

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.Semantic proximity Read ↗

Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data.Semantic proximity Read ↗

PNPLA3 I148M and Hepatocellular Carcinoma.Semantic proximity Read ↗

PNPLA3 I148M variant and hepatocellular carcinoma: a common genetic variant for a rare disease.Semantic proximity Read ↗

Genetics and epigenetics of NAFLD and NASH: Clinical impact.Semantic proximity Read ↗

PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma.Semantic proximity Read ↗

PNPLA3 Genotype and Clinical Factors Impact Hepatocellular Carcinoma Risk: Findings From a Prospective Cohort Study.Semantic proximity Read ↗

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease.Semantic proximity Read ↗

The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.Semantic proximity Read ↗

Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors.Semantic proximity Read ↗

PNPLA3 polymorphisms and risk of hepatic and extrahepatic outcomes in MASLD: A meta-analysis of observational studies.Semantic proximity Read ↗

Association and impact of SNPs in PNPLA3, TM6SF2 and MBOAT7 genes on prognosis factors of hepatocellular carcinoma with non-viral etiologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.