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Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis

22 Nov 2022

Abstract excerpt

BACKGROUND & AIMS: Identifying individuals at higher risk of developing hepatocellular carcinoma (HCC) is pivotal to improve the performance of surveillance strategies. Herein, we aimed to evaluate the ability of single nucleotide polymorphisms (SNPs) to refine HCC risk stratification. METHODS: Six SNPs in PNPLA3, TM6SF2, HSD17B13, APOE, and MBOAT7 affecting lipid turnover and one variant involved in the...

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Share to Genetic Associations and Epidemiology
Share to Hepatocellular Carcinoma Treatment and Prognosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36427656
DOI: 10.1016/j.jhep.2022.11.003

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