Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis.

Genes and immunity - 1 Jan 2017

Seshadri C, Thuong N T T, Mai N T H, Bang N D, Chau T T H, Lewinsohn D M, Thwaites G E, Dunstan S J, Hawn T R

Abstract excerpt

The MR1 antigen-presenting system is conserved among mammals and enables T cells to recognize small molecules produced by bacterial pathogens, including Mycobacterium tuberculosis (M.tb). However, it is not known whether MR1-mediated antigen presentation is important for protective immunity against mycobacterial disease. We hypothesized that genetic control of MR1 expression correlates with clinical outcomes of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Minor Histocompatibility Antigens

Share to Mycobacterium tuberculosis

Share to Prognosis

Share to Tuberculosis, Pulmonary

Share to Vietnam

Source

Open in PubMed Open full text

Identifiers

PMID: 27881839
DOI: 10.1038/gene.2016.41
PMCID: PMC5269436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis.PMID 27881839Read ↗

<i>MUC5AC</i> genetic variation is associated with tuberculosis meningitis CSF cytokine responses and mortalitySemantic proximity Read ↗

Polymorphic allele of human MRC1 confer protection against tuberculosis in a Chinese population.Semantic proximity Read ↗

A polymorphism in human CD1A is associated with susceptibility to tuberculosis.Semantic proximity Read ↗

Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?Semantic proximity Read ↗

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis.Semantic proximity Read ↗

Genetic variants in MARCO are associated with the susceptibility to pulmonary tuberculosis in Chinese Han population.Semantic proximity Read ↗

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.Semantic proximity Read ↗

TLR1 Variant H305L Associated with Protection from Pulmonary Tuberculosis.Semantic proximity Read ↗

MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa.Semantic proximity Read ↗

TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam.Semantic proximity Read ↗

MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.Semantic proximity Read ↗

Toll-like receptor 1 variations influence susceptibility and immune response to Mycobacterium tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.