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Article

TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam.

Tuberculosis (Edinburgh, Scotland) - 1 Mar 2015

Graustein A D, Horne D J, Arentz M, Bang N D, Chau T T H, Thwaites G E, Caws M, Thuong N T T, Dunstan S J, Hawn T R

Abstract excerpt

Humans exposed to Mycobacterium tuberculosis (Mtb) show variation in susceptibility to infection and differences in tuberculosis (TB) disease outcome. Toll-like receptor 9 (TLR9) is a pattern recognition receptor that mediates recognition of Mtb and modulates Mtb-specific T-cell responses. Using a case-population design, we evaluated whether single nucleotide polymorphisms (SNPs) in the TLR9 gene region are...

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Source

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Identifiers

PMID: 25616954
DOI: 10.1016/j.tube.2014.12.009
PMCID: PMC4573533

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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