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Article

TLR1 Variant H305L Associated with Protection from Pulmonary Tuberculosis.

PloS one - 1 Jan 2016

Meyer Christian G, Reiling Norbert, Ehmen Christa, Ruge Gerd, Owusu-Dabo Ellis, Horstmann Rolf D, Thye Thorsten

Abstract excerpt

Toll like receptors (TLR) are key elements of the innate immune response and involved in the recognition of pathogens. To test common and rare TLR variants involved in susceptibility or resistance to infection with Mycobacterium tuberculosis we screened the exons of the genes encoding TLR 1, 2, 4, and the adaptor molecule TIRAP in more than 4500 tuberculosis (TB) cases and controls from Ghana. The analysis...

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Source

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Identifiers

PMID: 27214039
DOI: 10.1371/journal.pone.0156046
PMCID: PMC4877073

Genes

TLR1
TIRAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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