Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism in human CD1A is associated with susceptibility to tuberculosis.

Genes and immunity - 1 Jan 2014

Seshadri C, Thuong N T T, Yen N T B, Bang N D, Chau T T H, Thwaites G E, Dunstan S J, Hawn T R

Abstract excerpt

CD1 proteins are antigen-presenting molecules that evolved to present lipids rather than peptides to T cells. However, unlike major histocompatibility complex genes, CD1 genes show low rates of polymorphism and have not been clearly associated with human disease. We report that an intronic polymorphism in CD1A (rs411089) is associated with susceptibility to tuberculosis in two cohorts of Vietnamese adults...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antigens, CD1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Odds Ratio

Share to Polymorphism, Genetic

Share to T-Lymphocytes

Share to Tuberculosis

Share to Vietnam

Source

Open in PubMed Open full text

Identifiers

PMID: 24500401
DOI: 10.1038/gene.2014.5
PMCID: PMC3998877

Genes

CD1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in human CD1A is associated with susceptibility to tuberculosis.PMID 24500401Read ↗

Human CD1a deficiency is common and genetically regulated.Semantic proximity Read ↗

A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis.Semantic proximity Read ↗

Unbiased definition of a shared T-cell receptor motif enables population-based studies of tuberculosisSemantic proximity Read ↗

Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile.Semantic proximity Read ↗

Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profileSemantic proximity Read ↗

HLA class II sequence variants influence tuberculosis risk in populations of European ancestry.Semantic proximity Read ↗

CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease.Semantic proximity Read ↗

SLC11A1 genetic variation and low expression may cause immune response impairment in TB patients.Semantic proximity Read ↗

Human slc11a1 Gene Polymorphism Has the Propensity to Confer Susceptibility to M. Africanum TB Disease in GhanaSemantic proximity Read ↗

Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression.Semantic proximity Read ↗

CD36 and SR-B1 Polymorphisms Exhibit Distinct Association Patterns in Active and Latent TuberculosisSemantic proximity Read ↗

Polymorphism of human CD1 genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.