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Article

MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa.

Human molecular genetics - 15 Jan 2009

Thye Thorsten, Nejentsev Sergey, Intemann Christopher D, Browne Edmund N, Chinbuah Margaret Amanua, Gyapong John, Osei Ivy, Owusu-Dabo Ellis, Zeitels Lauren R, Herb Florian, Horstmann Rolf D, Meyer Christian G

Abstract excerpt

Current endeavour focuses on human genetic factors that contribute to susceptibility to or protection from tuberculosis (TB). Monocytes are crucial in containing Mycobacterium tuberculosis infection, and the monocyte chemoattractant protein-1 (MCP-1) cytokine plays a role in their recruitment to the site of infection. The G allele of the MCP-1 promoter polymorphism at position -2581 relative to the ATG...

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Identifiers

PMID: 18940815
DOI: 10.1093/hmg/ddn352
PMCID: PMC2638774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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