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Article

Polymorphic allele of human MRC1 confer protection against tuberculosis in a Chinese population.

International journal of biological sciences - 1 Jan 2012

Zhang Xing, Jiang Feng, Wei Liliang, Li Fujian, Liu Jiyan, Wang Chong, Zhao Menyuan, Jiang Tingting, Xu Dandan, Fan Dapeng, Sun Xiaojun, Li Ji-Cheng

Abstract excerpt

Mannose receptor is a member of the C-type lectin receptor family involved in pathogen molecular-pattern recognition, and plays a critical role in shaping host immune response. Single nucleotide polymorphisms (SNPs) in the MRC1 gene may affect expression levels and differences in the structure and function of proteins in different individuals, thereby affecting individual susceptibility to pulmonary tuberculosis....

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Source

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Identifiers

PMID: 22393309
DOI: 10.7150/ijbs.4047
PMCID: PMC3291854

Genes

MRC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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