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Article

Vamana Couples Fat Signaling to the Hippo Pathway.

Developmental cell - 24 Oct 2016

Misra Jyoti R, Irvine Kenneth D

Abstract excerpt

The protocadherins Dachsous and Fat initiate a signaling pathway that controls growth and planar cell polarity by regulating the membrane localization of the atypical myosin Dachs. How Dachs is regulated by Fat signaling has remained unclear. Here we identify the vamana gene as playing a crucial role in regulating membrane localization of Dachs and in linking Fat and Dachsous to Dachs regulation. Vamana, an...

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Identifiers

PMID: 27746048
DOI: 10.1016/j.devcel.2016.09.017
PMCID: PMC5102026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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