Article
Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila.
Development (Cambridge, England) - 1 Jul 2006
Mao Yaopan, Rauskolb Cordelia, Cho Eunjoo, Hu Wei-Li, Hayter Heather, Minihan Ginny, Katz Flora N, Irvine Kenneth D
Abstract excerpt
The dachs gene was first identified almost a century ago based on its requirements for appendage growth, but has been relatively little studied. Here, we describe the phenotypes of strong dachs mutations, report the cloning of the dachs gene, characterize the localization of Dachs protein, and investigate the relationship between Dachs and the Fat pathway. Mutation of dachs reduces, but does not abolish, the...
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