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Article

Drosophila lowfat, a novel modulator of Fat signaling.

Development (Cambridge, England) - 1 Oct 2009

Mao Yaopan, Kucuk Binnaz, Irvine Kenneth D

Abstract excerpt

The Fat-Hippo-Warts signaling network regulates both transcription and planar cell polarity. Despite its crucial importance to the normal control of growth and planar polarity, we have only a limited understanding of the mechanisms that regulate Fat. We report here the identification of a conserved cytoplasmic protein, Lowfat (Lft), as a modulator of Fat signaling. Drosophila Lft, and its human homologs LIX1 and...

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Source

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Identifiers

PMID: 19710173
DOI: 10.1242/dev.036152
PMCID: PMC2739141

Genes

LIX1
FAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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