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Article

Generation and Analysis of Cartilage-Specific CCN2 Overexpression in Transgenic Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Hattori Takako, Itoh Shinsuke, Takigawa Masaharu

Abstract excerpt

Recent progress in gene-editing technology has provided a strong impact for improved our understanding of molecular functions in living organisms. Here we describe our method to generate transgene-overexpressing mouse models, which method involves the use of tissue-specific promoters for analyzing a certain molecule (s) in special tissues. The protocol described in this chapter uses the Col2a1 promoter-enhancer,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27734391
DOI: 10.1007/978-1-4939-6430-7_32

Genes

CCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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