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Article

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development.

Development (Cambridge, England) - 1 Jun 2003

Ivkovic Sanja, Yoon Byeong S, Popoff Steven N, Safadi Fayez F, Libuda Diana E, Stephenson Robert C, Daluiski Aaron, Lyons Karen M

Abstract excerpt

Coordinated production and remodeling of the extracellular matrix is essential during development. It is of particular importance for skeletogenesis, as the ability of cartilage and bone to provide structural support is determined by the composition and organization of the extracellular matrix. Connective tissue growth factor (CTGF, CCN2) is a secreted protein containing several domains that mediate interactions...

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Source

Open in PubMed Open full text

Identifiers

PMID: 12736220
DOI: 10.1242/dev.00505
PMCID: PMC3360973

Genes

CCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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