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Article

CD200R/Foxp3-mediated signalling regulates microglial activation.

Scientific reports - 12 Oct 2016

Yi Min-Hee, Zhang Enji, Kim Jwa-Jin, Baek Hyunjung, Shin Nara, Kim Sena, Kim Sang Ryong, Kim Hang-Rae, Lee Sung Joong, Park Jin Bong, Kim Yonghyun, Kwon O-Yu, Lee Young Ho, Oh Sang-Ha, Kim Dong Woon

Abstract excerpt

The heterogeneity of microglial functions have either beneficial or detrimental roles in specific physiological or pathological environments. However, the details of what transcriptional mechanisms induce microglia to take beneficial phenotypes remain unknown. Here, we report that Foxp3 is essential for beneficial outcome of the microglial response and depends upon signalling by the immunoglobulin CD200 through...

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PMID: 27731341
DOI: 10.1038/srep34901
PMCID: PMC5059636

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STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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