Article
CD200 maintains the region-specific phenotype of microglia in the midbrain and its role in Parkinson's disease.
Glia - 1 Sept 2020
Wang Le, Gong Xiaoli, Liu Yang, Du Tianshu, Zhang Zhen, Zhang Ting, Wang Xiaomin
Abstract excerpt
Microglia are a specialized population of tissue macrophages in the mammalian brain. Microglial phenotype is tightly regulated by local environmental factors, although little is known about these factors and their region-preferred roles in regulating local neuroinflammatory responses. We hypothesized that microglia in different brain regions respond differently to neuroinflammatory stimulation and that CD200, an...
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