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Article

Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.

Acta crystallographica. Section F, Structural biology communications - 1 Oct 2016

Janowski Robert, Scanu Sandra, Niessing Dierk, Madl Tobias

Abstract excerpt

The mammalian glutathione peroxidase (GPx) family is a key component of the cellular antioxidative defence system. Within this family, GPx4 has unique features as it accepts a large class of hydroperoxy lipid substrates and has a plethora of biological functions, including sperm maturation, regulation of apoptosis and cerebral embryogenesis. In this paper, the structure of the cytoplasmic isoform of mouse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27710939
DOI: 10.1107/S2053230X16013686
PMCID: PMC5053159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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