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Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3

6 Oct 2016

Abstract excerpt

A major arm of cellular innate immunity is type I interferon (IFN), represented by IFN-α and IFN-β. Type I IFN transcriptionally induces a large number of cellular genes, collectively known as IFN-stimulated gene (ISG) proteins, which act as antivirals. The IFIT (interferon-induced proteins with tetratricopeptide repeats) family proteins constitute a major subclass of ISG proteins and are characterized by...

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PMID: 27707917
DOI: 10.1128/jvi.01551-16

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