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Identification of Five Interferon-Induced Cellular Proteins That Inhibit West Nile Virus and Dengue Virus Infections

10 Jun 2010

Abstract excerpt

Interferons (IFNs) are key mediators of the host innate antiviral immune response. To identify IFN-stimulated genes (ISGs) that instigate an antiviral state against two medically important flaviviruses, West Nile virus (WNV) and dengue virus (DENV), we tested 36 ISGs that are commonly induced by IFN-alpha for antiviral activity against the two viruses. We discovered that five ISGs efficiently suppressed WNV...

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PMID: 20534863
DOI: 10.1128/jvi.02199-09

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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