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More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins

21 Nov 2017

Abstract excerpt

The first responders of human antiviral immunity are components of the intrinsic immune response that reside within each and every one of our cells. This cell-autonomous arsenal consists of nucleic acid sensors and antiviral effectors strategically placed by evolution to detect and restrict invading viruses. While some factors are present at baseline to allow for constant surveillance of the cell interior, others...

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PMID: 29162141
DOI: 10.1186/s12977-017-0377-y

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