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Article

Interferon induced IFIT family genes in host antiviral defense.

International journal of biological sciences - 1 Jan 2013

Zhou Xiang, Michal Jennifer J, Zhang Lifan, Ding Bo, Lunney Joan K, Liu Bang, Jiang Zhihua

Abstract excerpt

Secretion of interferons (IFNs) from virus-infected cells is a hallmark of host antiviral immunity and in fact, IFNs exert their antiviral activities through the induction of antiviral proteins. The IFN-induced protein with tetratricopeptide repeats (IFITs) family is among hundreds of IFN-stimulated genes. This family contains a cluster of duplicated loci. Most mammals have IFIT1, IFIT2, IFIT3 and IFIT5; however,...

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Adaptor Proteins, Signal Transducing
Carrier Proteins
Host-Pathogen Interactions
Interferons
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA-Binding Proteins

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PMID: 23459883
DOI: 10.7150/ijbs.5613
PMCID: PMC3584916

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