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The emerging roles of IFIT3 in antiviral innate immunity and cellular biology

28 Oct 2022

Abstract excerpt

The interferon-inducible protein with tetrapeptide repeats 3 (IFIT3) is one of the most important members in both the IFIT family and interferon-stimulated genes family. IFIT3 has typical features of the IFIT family in terms of gene and protein structures, and is able to be activated through the classical PRRs-IFN-JAK/STAT pathway. A variety of viruses can induce the expression of IFIT3, which in turn inhibits...

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PMID: 36305096
DOI: 10.1002/jmv.28259

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