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Article

Analysis of molecular alterations in laterally spreading tumors of the colorectum.

Journal of gastroenterology - 1 Jun 2017

Sugai Tamotsu, Habano Wataru, Takagi Ryo, Yamano Hiroo, Eizuka Makoto, Arakawa Noriyuki, Takahashi Yayoi, Yamamoto Eiichiro, Kawasaki Keisuke, Yanai Syunichi, Ishida Kazuyuki, Suzuki Hiromu, Matsumoto Takayuki

Abstract excerpt

BACKGROUND: Colorectal laterally spreading tumors (LSTs) are classified into LST-Gs and LST-NGs, according to macroscopic findings. In the present study, we determined the genetic and epigenetic alterations within colorectal LSTs and protruding adenomas. METHODS: A crypt isolation method was used to isolate DNA from tumors and normal glands of 73 macroscopically verified colorectal LSTs (histologically defined...

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Source

Identifiers

PMID: 27704264
DOI: 10.1007/s00535-016-1269-y

Genes

APC
KRAS
MLH1
SALL4
SFRP1
ZFP64
BRAF
DKK1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of molecular alterations in laterally spreading tumors of the colorectum.PMID 27704264Read ↗

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