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Article

Laterally spreading type of colorectal adenoma exhibits a unique methylation phenotype and K-ras mutations.

Gastroenterology - 1 Aug 2006

Hiraoka Sakiko, Kato Jun, Tatsukawa Masashi, Harada Keita, Fujita Hideyuki, Morikawa Tamiya, Shiraha Hidenori, Shiratori Yasushi

Abstract excerpt

BACKGROUND & AIMS: Laterally spreading tumors (LST), characterized by superficial extension along the colonic lumen, have recently been detected by colonoscopy. However, genetic and epigenetic characteristics of these tumors were scarcely reported. METHODS: A total of 205 sporadic colorectal adenoma tissues (157 protruded-type, 23 granular-type LST (G-LST), 12 flat-type LST (F-LST), and 13 flat-type smaller than...

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PMID: 16890591
DOI: 10.1053/j.gastro.2006.04.027

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Source receipt: pubmed, retrieved 7 Sept 2026.

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