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Article

Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer.

International journal of cancer - 1 Dec 2016

Takahashi Yayoi, Sugai Tamotsu, Habano Wataru, Ishida Kazuyuki, Eizuka Makoto, Otsuka Koki, Sasaki Akira, Takayuki Matsumoto, Morikawa Takanori, Unno Michiaki, Suzuki Hiromu

Abstract excerpt

Differences in the pathogenesis of microsatellite stable (MSS) sporadic colorectal cancers (CRCs) between left-sided CRC (LC) and right-sided CRC (RC) have not been clarified. To identify pathogenesis-related genomic differences between MSS CRCs within the two locations, we performed a comprehensive molecular analysis using crypt isolation with samples from 92 sporadic CRCs. Microsatellite instability (MSI; high...

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Identifiers

PMID: 27509333
DOI: 10.1002/ijc.30377
PMCID: PMC5096113

Genes

KRAS
BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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