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Article

Hypermethylation status of APC inversely correlates with the presence of submucosal invasion in laterally spreading colorectal tumors.

Molecular carcinogenesis - 1 Jan 2008

Hashimoto Kazuo, Shimizu Yoshihisa, Suehiro Yutaka, Okayama Naoko, Hashimoto Shinichi, Okada Toshiyuki, Hiura Mikako, Ueno Koji, Hazama Shoichi, Higaki Shingo, Hamanaka Yuichiro, Oka Masaaki, Sakaida Isao, Hinoda Yuji

Abstract excerpt

Little is known about epigenetic alterations in laterally spreading colorectal tumors (LSTs). The goal of the present study was to elucidate the epigenetic background of LSTs and compare the methylation status of DNA CpG islands (CGIs) with clinicopathologic features. Methylation of MINT1, MINT2,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17620311
DOI: 10.1002/mc.20363

Genes

APC
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17620311-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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