The Role of BDNF in the Development of Fear Learning.

doi:10.1002/da.22497

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Article

The Role of BDNF in the Development of Fear Learning.

Depression and anxiety - 1 Oct 2016

Dincheva Iva, Lynch Niccola B, Lee Francis S

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a growth factor that is dynamically expressed in the brain across postnatal development, regulating neuronal differentiation and synaptic plasticity. The neurotrophic hypothesis of psychiatric mood disorders postulates that in the adult brain, decreased BDNF levels leads to altered neural plasticity, contributing to disease. Although BDNF has been established as a key...

Topics

Adolescent
Adult
Animals
Anxiety Disorders
Brain
Brain-Derived Neurotrophic Factor
Child
Conditioning, Classical
Depressive Disorder
Fear
Humans
Learning
Mice
Nerve Net
Neuronal Plasticity
Polymorphism, Single Nucleotide

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Open in PubMed Open full text

Identifiers

PMID: 27699937
DOI: 10.1002/da.22497
PMCID: PMC5089164

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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