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Article

Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice.

The American journal of psychiatry - 1 Dec 2017

Dincheva Iva, Yang Jianmin, Li Anfei, Marinic Tina, Freilingsdorf Helena, Huang Chienchun, Casey B J, Hempstead Barbara, Glatt Charles E, Lee Francis S, Bath Kevin G, Jing Deqiang

Abstract excerpt

OBJECTIVE: Adolescence is a developmental stage in which the incidence of psychiatric disorders, such as anxiety disorders, peaks. Selective serotonin reuptake inhibitors (SSRIs) are the main class of agents used to treat anxiety disorders. However, the impact of SSRIs on the developing brain during adolescence remains unknown. The authors assessed the impact of developmentally timed SSRI administration in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29084453
DOI: 10.1176/appi.ajp.2017.15121592
PMCID: PMC5711544

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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