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Article

The brain-derived neurotrophic factor VAL68MET polymorphism modulates how developmental ethanol exposure impacts the hippocampus.

Genes, brain, and behavior - 1 Mar 2019

Bird C W, Baculis B C, Mayfield J J, Chavez G J, Ontiveros T, Paine D J, Marks A J, Gonzales A L, Ron D, Valenzuela C F

Abstract excerpt

Prenatal exposure to alcohol causes a wide range of deficits known as fetal alcohol spectrum disorders (FASDs). Many factors determine vulnerability to developmental alcohol exposure including timing and pattern of exposure, nutrition and genetics. Here, we characterized how a prevalent single nucleotide polymorphism in the human brain-derived neurotrophic factor (BDNF) gene (val66met) modulates FASDs severity....

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Source

Open in PubMed Open full text

Identifiers

PMID: 29691979
DOI: 10.1111/gbb.12484
PMCID: PMC6291361

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The brain-derived neurotrophic factor VAL68MET polymorphism modulates how developmental ethanol exposure impacts the hippocampus.PMID 29691979Read ↗

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