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Article

Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits.

Aging cell - 1 Feb 2017

Kulminski Alexander M, Kernogitski Yelena, Culminskaya Irina, Loika Yury, Arbeev Konstantin G, Bagley Olivia, Duan Matt, Arbeeva Liubov, Ukraintseva Svetlana V, Wu Deqing, Stallard Eric, Yashin Anatoliy I

Abstract excerpt

Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age-related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogeneous, age-related traits driven by the elusive role of evolution in their properties. We analyzed in detail the associations of rs693 and rs562338 polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over
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Identifiers

PMID: 27683205
DOI: 10.1111/acel.12526
PMCID: PMC5242299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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