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Article

The role of lipid-related genes, aging-related processes, and environment in healthspan.

Aging cell - 1 Apr 2013

Kulminski Alexander M, Culminskaya Irina, Arbeev Konstantin G, Ukraintseva Svetlana V, Stallard Eric, Arbeeva Liubov, Yashin Anatoli I

Abstract excerpt

The inherent complexity of aging-related traits can temper progress in unraveling the genetic origins of healthspan. We focus on two generations in the Framingham Heart Study, the original (FHS) and offspring (FHSO) cohorts, to determine whether aging-related processes in changing environments can substantially impact the role of lipid-related genes discovered in candidate gene (the apolipoprotein E (APOE) e2/3/4...

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Source

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Identifiers

PMID: 23320904
DOI: 10.1111/acel.12046
PMCID: PMC3602307

Genes

APOB
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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