Article
Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk.
International journal of epidemiology - 1 Oct 2004
Keavney Bernard, Palmer Alison, Parish Sarah, Clark Sarah, Youngman Linda, Danesh John, McKenzie Colin, Delépine Marc, Lathrop Mark, Peto Richard, Collins Rory
Abstract excerpt
BACKGROUND: Blood lipid concentrations are causally related to the risk of coronary heart disease (CHD). Various associations between CHD risk and genes that moderately affect plasma lipid levels have been described, but previous studies have typically involved too few 'cases' to assess these associations reliably. METHODS: The present study involves 4685 cases of myocardial infarction (MI) and 3460 unrelated...
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